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The PA3177 Gene Encodes an Active Diguanylate Cyclase That Contributes to Biofilm Antimicrobial Tolerance but Not Biofilm Formation by Pseudomonas aeruginosa

A hallmark of biofilms is their heightened resistance to antimicrobial agents. Recent findings suggested a role for bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) in the susceptibility of bacteria to antimicrobial agents; however, no c-di-GMP modulating enzyme(s) contributing to the drug tolerance phenot...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Poudyal, Bandita, Sauer, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153807/
https://ncbi.nlm.nih.gov/pubmed/30082282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01049-18
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