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Past and Present Perspectives on β-Lactamases

β-Lactamases, the major resistance determinant for β-lactam antibiotics in Gram-negative bacteria, are ancient enzymes whose origins can be traced back millions of years ago. These well-studied enzymes, currently numbering almost 2,800 unique proteins, initially emerged from environmental sources, m...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Hovedforfatter: Bush, Karen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153792/
https://ncbi.nlm.nih.gov/pubmed/30061284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01076-18
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