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Rhythmic Diurnal Synthesis and Signaling of Retinoic Acid in the Rat Pineal Gland and Its Action to Rapidly Downregulate ERK Phosphorylation

Vitamin A is important for the circadian timing system; deficiency disrupts daily rhythms in activity and clock gene expression, and reduces the nocturnal peak in melatonin in the pineal gland. However, it is currently unknown how these effects are mediated. Vitamin A primarily acts via the active m...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Ashton, Anna, Stoney, Patrick N., Ransom, Jemma, McCaffery, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153719/
https://ncbi.nlm.nih.gov/pubmed/29520716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-0964-5
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