Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

BACKGROUND: Untargeted mass spectrometry (MS)-based metabolomics data often contain missing values that reduce statistical power and can introduce bias in biomedical studies. However, a systematic assessment of the various sources of missing values and strategies to handle these data has received li...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Metabolomics
Prif Awduron: Do, Kieu Trinh, Wahl, Simone, Raffler, Johannes, Molnos, Sophie, Laimighofer, Michael, Adamski, Jerzy, Suhre, Karsten, Strauch, Konstantin, Peters, Annette, Gieger, Christian, Langenberg, Claudia, Stewart, Isobel D., Theis, Fabian J., Grallert, Harald, Kastenmüller, Gabi, Krumsiek, Jan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153696/
https://ncbi.nlm.nih.gov/pubmed/30830398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-018-1420-2
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