Prioritized High-Confidence Risk Genes for Intellectual Disability Reveal Molecular Convergence During Brain Development

Dissecting the genetic susceptibility to intellectual disability (ID) based on de novo mutations (DNMs) will aid our understanding of the neurobiological and genetic basis of ID. In this study, we identify 63 high-confidence ID genes with q-values < 0.1 based on four background DNM rates and codi...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Liu, Zhenwei, Zhang, Na, Zhang, Yu, Du, Yaoqiang, Zhang, Tao, Li, Zhongshan, Wu, Jinyu, Wang, Xiaobing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153320/
https://ncbi.nlm.nih.gov/pubmed/30279698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00349
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