The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development

Tooth morphogenesis is initiated by reciprocal interactions between the ectoderm and neural crest–derived mesenchyme. During tooth development, tooth cusps are regulated by precise control of proliferation of cell clusters, termed enamel knots, that are present among dental epithelial cells. The int...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Han, Xue, Yoshizaki, Keigo, Miyazaki, Kanako, Arai, Chieko, Funada, Keita, Yuta, Tomomi, Tian, Tian, Chiba, Yuta, Saito, Kan, Iwamoto, Tsutomu, Yamada, Aya, Takahashi, Ichiro, Fukumoto, Satoshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153296/
https://ncbi.nlm.nih.gov/pubmed/30089653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003373
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