4C-seq characterization of Drosophila BEAF binding regions provides evidence for highly variable long-distance interactions between active chromatin

Chromatin organization is crucial for nuclear functions such as gene regulation, DNA replication and DNA repair. Insulator binding proteins, such as the Drosophila Boundary Element-Associated Factor (BEAF), are involved in chromatin organization. To further understand the role of BEAF, we detected c...

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Publicado en:PLoS One
Autores principales: Shrestha, Shraddha, Oh, Dong-Ha, McKowen, J. Keller, Dassanayake, Maheshi, Hart, Craig M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152978/
https://ncbi.nlm.nih.gov/pubmed/30248133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203843
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