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Preserved Structural Network Organization Mediates Pathology Spread in Alzheimer’s Disease Spectrum Despite Loss of White Matter Tract Integrity

Models of Alzheimer’s disease (AD) hypothesize stereotyped progression via white matter (WM) fiber connections, most likely via trans-synaptic transmission of toxic proteins along neuronal pathways. An important question in the field is whether and how organization of fiber pathways is affected by d...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Powell, Fon, Tosun, Duygu, Sadeghi, Roksana, Weiner, Michael, Raj, Ashish
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152926/
https://ncbi.nlm.nih.gov/pubmed/29578480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170798
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