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Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion
Cleft palate is one of the most common craniofacial congenital defects in humans. It is associated with multiple genetic and environmental risk factors, including mutations in the genes encoding signaling molecules in the sonic hedgehog (Shh) pathway, which are risk factors for cleft palate in both...
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| Опубликовано в: : | Dev Biol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152919/ https://ncbi.nlm.nih.gov/pubmed/29981310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.07.003 |
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