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Loss of response to anti-tumor necrosis factor alpha therapy in Crohn’s disease is not associated with emergence of novel inflammatory pathways
BACKGROUND: While monoclonal antibodies against tumor necrosis factor-α (TNFα) are effective in treating Crohn’s disease (CD), approximately one-third of patients lose response. The mechanisms underlying this loss of response remain elusive. AIM: We sought to determine if novel biological pathways,...
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| Publicado no: | Dig Dis Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152907/ https://ncbi.nlm.nih.gov/pubmed/29372477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-018-4932-8 |
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