Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage

Matrix metalloproteinases-2 and -9 (MMP-2/-9) are key tissue remodeling enzymes that have multiple overlapping activities critical for wound healing and tumor progression in vivo. To overcome issues of redundancy in studying their functions in vivo, we created MMP-2/-9 double knockout (DKO) mice in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hingorani, Dina V., Lippert, Csilla N., Crisp, Jessica L., Savariar, Elamprakash N., Hasselmann, Jonathan P. C., Kuo, Christopher, Nguyen, Quyen T., Tsien, Roger Y., Whitney, Michael A., Ellies, Lesley G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152858/
https://ncbi.nlm.nih.gov/pubmed/30248101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198464
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