Impact of MTHFR (C677T) gene polymorphism on antiepileptic drug monotherapy in North Indian epileptic population

BACKGROUND AND OBJECTIVES: Antiepileptic drugs (AEDs) are known to interfere with homocysteine metabolism. Hyperhomocysteinemia may be a risk factor associated in the long-term treatment with AEDs. Both genetic and non-genetic factors are responsible for hyperhomocysteinemia. MTHFR C677T. Polymorphi...

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Udgivet i:Ann Saudi Med
Main Authors: Munisamy, Murali, Al-Gahtany, Mubarak, Tripathi, Manjari, Subbiah, Vivekanandhan
Format: Artigo
Sprog:Inglês
Udgivet: King Faisal Specialist Hospital and Research Centre 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152547/
https://ncbi.nlm.nih.gov/pubmed/26142939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5144/0256-4947.2015.51
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