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Phosphate-Linked Silibinin Dimers (PLSd): New Promising Modified Metabolites

By exploiting the regioselective protection of the hydroxyl groups of silibinin along with the well-known phosphoramidite chemistry, we have developed an efficient strategy for the synthesis of new silibinin-modified species, which we have named Phosphate-Linked Silibinin Dimers (PLSd), in which the...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Romanucci, Valeria, Gravante, Raffaele, Cimafonte, Martina, Di Marino, Cinzia, Mailhot, Gilles, Brigante, Marcello, Zarrelli, Armando, Di Fabio, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152259/
https://ncbi.nlm.nih.gov/pubmed/28800072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081323
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