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A Divergent Role of COOH-Terminal Domains in Nurr1 and Nur77 Transactivation

Orphan nuclear receptors such as Nurr1 and Nur77 have conserved amino acid sequences in the zinc finger DNA binding domains and similar COOH-terminal regions, but have no known ligands. These receptors can bind DNA sequences (response elements) as monomers and can also heterodimerize with the retino...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Castillo, Susan O., Xiao, Qianxun, Kostrouch, Zdenek, Dozin, Beatrice, Nikodem, Vera M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151941/
https://ncbi.nlm.nih.gov/pubmed/9572393
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