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The susceptibility of cochlear outer hair cells to cyclodextrin is not related to their electromotile activity
Niemann-Pick Type C1 (NPC1) disease is a fatal neurovisceral disorder caused by dysfunction of NPC1 protein, which plays a role in intracellular cholesterol trafficking. The cholesterol-chelating agent, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is currently undergoing clinical trials for treatment of...
Gardado en:
| Publicado en: | Acta Neuropathol Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6151916/ https://ncbi.nlm.nih.gov/pubmed/30249300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0599-9 |
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