Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design

Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an excellent tool in the optimization of a chromatographic method, because it is possible quickly change factors such as temperature, mobile phase com...

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Publicado no:Molecules
Main Authors: Azevedo de Brito, Wanessa, Gomes Dantas, Monique, Andrade Nogueira, Fernando Henrique, Ferreira da Silva-Júnior, Edeildo, Xavier de Araújo-Júnior, João, de Aquino, Thiago Mendonça, Adélia Nogueira Ribeiro, Êurica, da Silva Solon, Lilian Grace, Soares Aragão, Cícero Flávio, Barreto Gomes, Ana Paula
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151785/
https://ncbi.nlm.nih.gov/pubmed/28867762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22091394
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