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Effect of Sipjeondaebo-Tang on the Pharmacokinetics of S-1, an Anticancer Agent, in Rats Evaluated by Population Pharmacokinetic Modeling

S-1 (TS-1(®)) is an oral fluoropyrimidine anticancer agent containing tegafur, oteracil, and gimeracil. Sipjeondaebo-tang (SDT) is a traditional oriental herbal medicine that has potential to alleviate chemotherapy-related adverse effects. The aim of the present study was to evaluate the effect of S...

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Publicat a:Molecules
Autors principals: Kim, Tae Hwan, Shin, Soyoung, Shin, Jeong Cheol, Bulitta, Jürgen B., Weon, Kwon-Yeon, Yoo, Sun Dong, Park, Gi-Young, Jeong, Seok Won, Kwon, Dong Rak, Min, Byung Sun, Woo, Mi Hee, Shin, Beom Soo
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151713/
https://ncbi.nlm.nih.gov/pubmed/28880240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22091488
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