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Design, Synthesis, Antimycobacterial Evaluation, and In Silico Studies of 3-(Phenylcarbamoyl)-pyrazine-2-carboxylic Acids

Pyrazinamide, the first-line antitubercular drug, has been regarded the basic component of tuberculosis treatment for over sixty years. Researchers have investigated its effect on Mycobacterium tuberculosis for this long time, and as a result, new potential targets of pyrazinamide or its active form...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Semelková, Lucia, Janošcová, Petra, Fernandes, Carlos, Bouz, Ghada, Janďourek, Ondřej, Konečná, Klára, Paterová, Pavla, Navrátilová, Lucie, Kuneš, Jiří, Doležal, Martin, Zitko, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151461/
https://ncbi.nlm.nih.gov/pubmed/28880230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22091491
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