Antibacterial Synthetic Peptides Derived from Bovine Lactoferricin Exhibit Cytotoxic Effect against MDA-MB-468 and MDA-MB-231 Breast Cancer Cell Lines

Linear, dimeric, tetrameric, and cyclic peptides derived from lactoferricin B, containing the RRWQWR motif, were designed, synthesized, purified, and characterized using RP-HPLC chromatography and MALDI-TOF mass spectrometry. The antibacterial activity of the designed peptides against E. coli (ATCC...

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Vydáno v:Molecules
Hlavní autoři: Vargas Casanova, Yerly, Rodríguez Guerra, Jorge Antonio, Umaña Pérez, Yadi Adriana, Leal Castro, Aura Lucía, Almanzar Reina, Giovanni, García Castañeda, Javier Eduardo, Rivera Monroy, Zuly Jenny
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151437/
https://ncbi.nlm.nih.gov/pubmed/28961215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101641
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