Phase 2b placebo-controlled trial of M72/AS01(E) candidate vaccine to prevent active tuberculosis in adults

BACKGROUND: A tuberculosis vaccine to interrupt transmission is urgently needed. We assessed the safety and efficacy of the candidate tuberculosis vaccine, M72/AS01(E), against progression to bacteriologically-confirmed active pulmonary tuberculosis disease in adults with latent Mycobacterium tuberc...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Van Der Meeren, Olivier, Hatherill, Mark, Nduba, Videlis, Wilkinson, Robert J, Muyoyeta, Monde, Van Brakel, Elana, Ayles, Helen M, Henostroza, German, Thienemann, Friedrich, Scriba, Thomas J., Diacon, Andreas, Blatner, Gretta L., Demoitié, Marie-Ange, Tameris, Michele, Malahleha, Mookho, Innes, James C., Hellstrom, Elizabeth, Martinson, Neil, Singh, Tina, Akite, Elaine Jacqueline, Khatoon, Aisha, Bollaerts, Anne, Ginsberg, Ann M., Evans, Thomas G., Gillard, Paul, Tait, Dereck R.
Formato: Artigo
Idioma:Inglês
Publicado em: Massachusetts Medical Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151253/
https://ncbi.nlm.nih.gov/pubmed/30280651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1803484
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