Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

Immune-based therapies for cancer are generating substantial interest because of the success of immune checkpoint inhibitors. This study aimed to enhance anticancer immunity by exploiting the capacity of dendritic cells (DCs) to initiate T cell immunity by efficient uptake and presentation of endocy...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Dhodapkar, Madhav V., Sznol, Mario, Zhao, Biwei, Wang, Ding, Carvajal, Richard D., Keohan, Mary L., Chuang, Ellen, Sanborn, Rachel E., Lutzky, Jose, Powderly, John, Kluger, Harriet, Tejwani, Sheela, Green, Jennifer, Ramakrishna, Venky, Crocker, Andrea, Vitale, Laura, Yellin, Michael, Davis, Thomas, Keler, Tibor
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151129/
https://ncbi.nlm.nih.gov/pubmed/24739759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008068
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