Anti-inflammatory effects of minocycline are mediated by retinoid signaling

BACKGROUND: Minocycline is a lipophilic tetracycline of increasing appeal in neuroscience as it inhibits microglial activation, a mechanism involved in numerous neuropsychiatric disorders. Own data point towards retinoid-mediated effects of minocycline in murine brain and skin, and towards a vicious...

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Bibliographic Details
Published in:BMC Neurosci
Main Authors: Clemens, Vera, Regen, Francesca, Le Bret, Nathalie, Heuser, Isabella, Hellmann-Regen, Julian
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151010/
https://ncbi.nlm.nih.gov/pubmed/30241502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0460-x
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