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Progressive multiple sequence alignment with indel evolution

BACKGROUND: Sequence alignment is crucial in genomics studies. However, optimal multiple sequence alignment (MSA) is NP-hard. Thus, modern MSA methods employ progressive heuristics, breaking the problem into a series of pairwise alignments guided by a phylogeny. Changes between homologous characters...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Maiolo, Massimo, Zhang, Xiaolei, Gil, Manuel, Anisimova, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151001/
https://ncbi.nlm.nih.gov/pubmed/30241460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2357-1
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