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Developmental Trajectories of the Orbital Frontal Cortex and Anhedonia in Middle Childhood and Risk for Substance Use in Adolescence in a Longitudinal Sample of Depressed and Healthy Preschoolers

OBJECTIVE: Deficits in reward processing are established in mood and substance use and are known risk factors for these disorders. Volume reductions of the orbital frontal cortex and the striatum, regions that subserve neural response to reward, have been identified related to anhedonia in depressiv...

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Detalhes bibliográficos
Publicado no:Am J Psychiatry
Main Authors: Luby, Joan L., Agrawal, Arpana, Belden, Andy, Whalen, Diana, Tillman, Rebecca, Barch, Deanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150861/
https://ncbi.nlm.nih.gov/pubmed/29558817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2018.17070777
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