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Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators
A new series of 2-alkyloxy-pyridine-3-carbonitrile-benzofuran hybrids (4a–x) was synthesized. All the new derivatives were examined via the standard technique for their vasodilation activity. Some of the investigated compounds exhibited a remarkable activity, with compounds 4w, 4e, 4r, 4s, 4f and 4g...
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| Publié dans: | Molecules |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6150240/ https://ncbi.nlm.nih.gov/pubmed/29072621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22111820 |
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