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Inhibition of bcl-2 and cox-2 Protein Expression after Local Application of a New Carmustine-Loaded Clinoptilolite-Based Delivery System in a Chemically Induced Skin Cancer Model in Mice

Our research has focused on in vitro and in vivo evaluations of a new Carmustine (BCNU)-loaded clinoptilolite-based delivery system. Two clinoptilolite ionic forms—hydrogen form (HCLI) and sodium form (NaCLI)—were prepared, allowing a loading degree of about 5–6 mg BCNU/g of zeolite matrix due to th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ghiciuc, Cristina Mihaela, Strat, Aurel Lulu, Ochiuz, Lacramioara, Lupusoru, Catalina Elena, Ignat, Maria, Vasile, Aurelia, Grigorovici, Alexandru, Stoleriu, Iulian, Solcan, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150160/
https://ncbi.nlm.nih.gov/pubmed/29156646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22112014
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