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Multi Component Reactions under Increased Pressure: On the Mechanism of Formation of Pyridazino[5,4,3-de][1,6]naphthyridine Derivatives by the Reaction of Malononitrile, Aldehydes and 2-Oxoglyoxalarylhydrazones in Q-Tubes

Efficient synthesis of phenanthridin-6(5H)-one derivatives 12a–n in a four-component reaction of aldehyde hydrazone, aromatic aldehydes and malononitrile in Q-Tubes is reported. The results showed that the methodology has the advantage of being a one-pot synthesis of tricyclic systems in good yields...

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Publicado en:Molecules
Main Authors: AL-Johani, Majdah A., Al-Zaydi, Khadijah M., Mousally, Sameera M., Alqahtani, Norah F., Elnagdi, Noha Hilmy, Elnagdi, Mohamed H.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149974/
https://ncbi.nlm.nih.gov/pubmed/29194410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22122114
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