Fluorinated Analogs of Organosulfur Compounds from Garlic (Allium sativum): Synthesis, Chemistry and Anti-Angiogenesis and Antithrombotic Studies

We describe the synthesis, reactivity, and antithrombotic and anti-angiogenesis activity of difluoroallicin (S-(2-fluoroallyl) 2-fluoroprop-2-ene-1-sulfinothioate) and S-2-fluoro-2-propenyl-l-cysteine, both easily prepared from commercially available 3-chloro-2-fluoroprop-1-ene, as well as the synth...

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Veröffentlicht in:Molecules
Hauptverfasser: Block, Eric, Bechand, Benjamin, Gundala, Sivaji, Vattekkatte, Abith, Wang, Kai, Mousa, Shaymaa S., Godugu, Kavitha, Yalcin, Murat, Mousa, Shaker A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149718/
https://ncbi.nlm.nih.gov/pubmed/29182588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22122081
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