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Conformational selectivity and high-affinity binding in the complexation of N-phenyl amides in water by a phenyl extended calix[4]pyrrole

We describe the synthesis of a tetrapyridinium phenyl extended calix[4]pyrrole that is soluble in neutral water solution at mM concentrations. We show that, in pure water, the synthesized calix[4]pyrrole receptor selectively binds the cis-(E) conformers of secondary N-phenyl-amides and tertiary N-me...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Escobar, L., Díaz-Moscoso, A., Ballester, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149442/
https://ncbi.nlm.nih.gov/pubmed/30288237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03034k
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