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A Simplified Procedure for Indole Alkaloid Extraction from Catharanthus roseus Combined with a Semi-synthetic Production Process for Vinblastine

Dried leaves of Catharanthus roseus were extracted with aqueous acidic 0.1 M solution of HCl. Alkaloid-embonate complexes were obtained as precipitates by treating the extract with an alkaline (NaOH) solution of embonic acid (4,4’-methylene-bis-3-hydroxynaphtalenecarboxylic acid). The precipitate ma...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Verma, Arvind, Laakso, Into, Seppänen-Laakso, Tuulikki, Huhtikangas, Aarre, Riekkola, Marja-Liisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149338/
https://ncbi.nlm.nih.gov/pubmed/17909486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/12071307
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