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Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics

The synthesis of nucleosides modified with an extra imidazole, carboxyl and hydroxyl group is described. These nucleosides can be incorporated into an oligonucleotide duplex, thus generating a novel type of serine protease mimic.

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Catry, Mieke A., Madder, Annemieke
Format: Artigo
Langue:Inglês
Publié: MDPI 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149322/
https://ncbi.nlm.nih.gov/pubmed/17693958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/12010114
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