Melatonin Upregulates Nuclear Factor Erythroid-2 Related Factor 2 (Nrf2) and Mediates Mitophagy to Protect Against Early Brain Injury After Subarachnoid Hemorrhage

BACKGROUND: The aim of this study was to investigate whether melatonin is involved in brain injury following subarachnoid hemorrhage (SAH). MATERIAL/METHODS: An SAH model was established and TUNEL assays were utilized to detect the effect of melatonin on cell apoptosis. Western blot analysis was use...

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Detalles Bibliográficos
Publicado en:Med Sci Monit
Main Authors: Sun, Bin, Yang, Song, Li, Shengli, Hang, Chunhua
Formato: Artigo
Idioma:Inglês
Publicado: International Scientific Literature, Inc. 2018
Assuntos:
Animal Study
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149238/
https://ncbi.nlm.nih.gov/pubmed/30210141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.909221
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