Synthesis of Novel Derivatives of4-Amino-3-(2-Furyl)-5-Mercapto-1,2,4-Triazole asPotential HIV-1 NNRTIs

A series of 5-alkylthio (2a-d), 4-arylideneamino (3a-d) and 4-arylideneamino-5-alkylthio derivatives (4a-f) of 4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazole (1) were synthesized by alkylation of the parent compound with alkyl halides and condensation with aldehydes, respectively. Sulfanyl dimers 5a-...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wu, Jingde, Liu, Xinyong, Cheng, Xianchao, Cao, Yuan, Wang, Defeng, Li, Zhong, Xu, Wenfang, Pannecouque, Christophe, Witvrouw, Myriam, De Clercq, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2007
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Full Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149092/
https://ncbi.nlm.nih.gov/pubmed/17960101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/12082003
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