Heterocycles [h]Fused onto 4-Oxoquinoline-3-Carboxylic Acid, Part IV. Convenient Synthesis of Substituted Hexahydro [1,4]Thiazepino[2,3-h]quinoline-9-carboxylic Acid and Its Tetrahydroquino[7,8-b]benzothiazepine Homolog †

Substituted [1,4]thiazepino[2,3-h]quinolinecarboxylic acid 3 is prepared by PPA-catalyzed thermal lactamization of the respective 8-amino-7-[(2-carboxyethyl)thio]-1,4-dihydroquinoline-3-carboxylic acid 9. The latter synthon is obtained by reduction of the 8-nitro-1,4-dihydroquinoline precursor 8 whi...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Al-Huniti, Mohammed H., El-Abadelah, Mustafa M., Zahra, Jalal A., Sabri, Salim S., Ingendoh, Arnd
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2007
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Full Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149087/
https://ncbi.nlm.nih.gov/pubmed/17960073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/12081558
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