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MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells

Triple negative breast cancer (TNBC) is a subtype of breast cancer with a poor prognosis and high mortality rate. The tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) plays an important role in cell proliferation and cell migration by negatively regulating the PI3K/Akt...

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Détails bibliographiques
Publié dans:Carcinogenesis
Auteurs principaux: Chai, Chengsen, Wu, Hong, Wang, Benfan, Eisenstat, David D, Leng, Roger P
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148990/
https://ncbi.nlm.nih.gov/pubmed/29985991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy092
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