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Synthesis and Anticancer Activities of Novel 1,4-Disubstituted Phthalazines

A series of novel 1-anilino-4-(arylsulfanylmethyl)phthalazines were designed and synthesized. The structures of all the compounds were confirmed by IR, (1)H-NMR, elemental analysis and MS. The analogues 1-(3-chloro-4-fluoroanilino)-4-(3,4-difluorophenylthio-methyl)phthalazine (12) and 1-(4-fluoro-3-...

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Publicat a:Molecules
Autors principals: Li, Juan, Zhao, Yan-Fang, Yuan, Xiao-Ye, Xu, Jing-Xiong, Gong, Ping
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148564/
https://ncbi.nlm.nih.gov/pubmed/17971729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11070574
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