Design and Synthesis of New 1,3,5‐Trisubstituted Triazines for the Treatment of Cancer and Inflammation

Low‐molecular‐weight synthetic molecules 1 with the general 2‐(fluorophenylamino)‐4,6‐disubstituted 1,3,5‐triazine structure and showing anti‐inflammatory and anticancer activities were explored. Structure–activity relationship studies demonstrated the importance of the aminopentyl chain, the 3‐ or...

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Опубликовано в: :ChemistryOpen
Главные авторы: Zacharie, Boulos, Abbott, Shaun D., Duceppe, Jean‐Simon, Gagnon, Lyne, Grouix, Brigitte, Geerts, Lilianne, Gervais, Liette, Sarra‐Bournet, François, Perron, Valérie, Wilb, Nicole, Penney, Christopher L., Laurin, Pierre
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148406/
https://ncbi.nlm.nih.gov/pubmed/30258746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201800136
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