Melatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells

Diabetes mellitus affects a large number of men of reproductive age and it usually leads to serious reproductive disorders. However, the underlying mechanisms and specific therapies still remain largely unknown. We observed Leydig cell loss in the testes of diabetic mice. Continuous high glycemic st...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Du, Zhaoyu, Xu, Shuanshuan, Hu, Shuxian, Yang, Hong, Zhou, Zhe, Sidhu, Kuldip, Miao, Yiliang, Liu, Zhonghua, Shen, Wei, Reiter, Russel J., Hua, Jinlian, Peng, Sha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148071/
https://ncbi.nlm.nih.gov/pubmed/30237484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0956-4
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