Vascularization converts the lineage fate of bone mesenchymal stem cells to endothelial cells in tissue-engineered bone grafts by modulating FGF2-RhoA/ROCK signaling

The prevascularization of tissue-engineered bone grafts (TEBGs) has been shown to accelerate capillary vessel ingrowth in bone defect remodeling and to enhance new bone formation. However, the exact mechanisms behind this positive effect remain unknown. Here, we report that basic fibroblast growth f...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Donglin, Cheng, Pengzhen, Jiang, Huijie, Cao, Tianqing, Wang, Jimeng, Gao, Yi, Lin, Yangjing, Wang, Chunmei, Zhang, Shuaishuai, Li, Junqin, Liu, Bin, Song, Yue, Yang, Liu, Pei, Guoxian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147920/
https://ncbi.nlm.nih.gov/pubmed/30237398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0999-6
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