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Asymmetric Synthesis Antimicrobial Activity of Some New Mono Bicyclic β-Lactams
Reaction of the amino acid D-phenylalanine ethyl ester (4) with cinnamaldehyde gave chiral Schiff base 5, which underwent an asymmetric Staudinger [2+2] cycloaddition reaction with phthalimidoacetyl chloride to give the monocyclic β-lactam 6 as a single stereoisomer. Ozonolysis of 6 followed by redu...
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| Publicado no: | Molecules |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6147359/ https://ncbi.nlm.nih.gov/pubmed/18007494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/91100939 |
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