Analysis of Complement-Mediated Lysis of Simian Immunodeficiency Virus (SIV) and SIV-Infected Cells Reveals Sex Differences in Vaccine-Induced Immune Responses in Rhesus Macaques

An effective human immunodeficiency virus (HIV) vaccine has yet to be developed, and defining immune correlates of protection against HIV infection is of paramount importance to inform future vaccine design. The complement system is a component of innate immunity that can directly lyse pathogens and...

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Bibliographic Details
Published in:J Virol
Main Authors: Miller-Novak, Leia K., Das, Jishnu, Musich, Thomas A., Demberg, Thorsten, Weiner, Joshua A., Venzon, David J., Mohanram, Venkatramanan, Vargas-Inchaustegui, Diego A., Tuero, Iskra, Ackerman, Margaret E., Alter, Galit, Robert-Guroff, Marjorie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146823/
https://ncbi.nlm.nih.gov/pubmed/30021899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00721-18
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