Analysis of Complement-Mediated Lysis of Simian Immunodeficiency Virus (SIV) and SIV-Infected Cells Reveals Sex Differences in Vaccine-Induced Immune Responses in Rhesus Macaques

An effective human immunodeficiency virus (HIV) vaccine has yet to be developed, and defining immune correlates of protection against HIV infection is of paramount importance to inform future vaccine design. The complement system is a component of innate immunity that can directly lyse pathogens and...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Miller-Novak, Leia K., Das, Jishnu, Musich, Thomas A., Demberg, Thorsten, Weiner, Joshua A., Venzon, David J., Mohanram, Venkatramanan, Vargas-Inchaustegui, Diego A., Tuero, Iskra, Ackerman, Margaret E., Alter, Galit, Robert-Guroff, Marjorie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146823/
https://ncbi.nlm.nih.gov/pubmed/30021899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00721-18
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