Sendai Virus V Protein Inhibits the Secretion of Interleukin-1β by Preventing NLRP3 Inflammasome Assembly

Inflammasomes play a key role in host innate immune responses to viral infection by caspase-1 (Casp-1) activation to facilitate interleukin-1β (IL-1β) secretion, which contributes to the host antiviral defense. The NLRP3 inflammasome consists of the cytoplasmic sensor molecule NLRP3, adaptor protein...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Komatsu, Takayuki, Tanaka, Yukie, Kitagawa, Yoshinori, Koide, Naoki, Naiki, Yoshikazu, Morita, Naoko, Gotoh, Bin, Yokochi, Takashi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2018
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146803/
https://ncbi.nlm.nih.gov/pubmed/30021903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00842-18
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