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The Apical Region of the Herpes Simplex Virus Major Capsid Protein Promotes Capsid Maturation

The herpesvirus capsid assembles in the nucleus as an immature procapsid precursor built around viral scaffold proteins. The event that initiates procapsid maturation is unknown, but it is dependent upon activation of the VP24 internal protease. Scaffold cleavage triggers angularization of the shell...

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Foilsithe in:J Virol
Main Authors: Ruhge, Laura L., Huet, Alexis G. E., Conway, James F., Smith, Gregory A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146679/
https://ncbi.nlm.nih.gov/pubmed/29976665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00821-18
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