Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets

BACKGROUND: Prostaglandins are products of the cyclooxygenase pathway, which is implicated in Parkinson’s disease (PD). Limited knowledge is available on mechanisms by which prostaglandins contribute to PD neurodegeneration. To address this gap, we focused on the prostaglandin PGD2/J2 signaling path...

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Publicat a:J Neuroinflammation
Autors principals: Corwin, Chuhyon, Nikolopoulou, Anastasia, Pan, Allen L., Nunez-Santos, Mariela, Vallabhajosula, Shankar, Serrano, Peter, Babich, John, Figueiredo-Pereira, Maria E.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146649/
https://ncbi.nlm.nih.gov/pubmed/30236122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1305-3
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