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RNAs as Proximity-Labeling Media for Identifying Nuclear Speckle Positions Relative to the Genome

It remains challenging to identify all parts of the nuclear genome that are in proximity to nuclear speckles, due to physical separation between the nuclear speckle cores and chromatin. We hypothesized that noncoding RNAs including small nuclear RNA (snRNAs) and Malat1, which accumulate at the perip...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Chen, Weizhong, Yan, Zhangming, Li, Simin, Huang, Norman, Huang, Xuerui, Zhang, Jin, Zhong, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146591/
https://ncbi.nlm.nih.gov/pubmed/30240742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.06.005
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