Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway

BACKGROUND: Complex mechanisms participate in microglial activation after a traumatic brain injury (TBI). TBI can induce autophagy and apoptosis in neurons and glial cells, and moderate hypothermia plays a protective role in the acute phase of TBI. In the present study, we evaluated the effect of TB...

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Detaylı Bibliyografya
Yayımlandı:J Neuroinflammation
Asıl Yazarlar: Zhang, Fengchen, Dong, Haiping, Lv, Tao, Jin, Ke, Jin, Yichao, Zhang, Xiaohua, Jiang, Jiyao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146525/
https://ncbi.nlm.nih.gov/pubmed/30236124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1315-1
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