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Sequence dependence of C-end rule peptides in binding and activation of neuropilin-1 receptor
Neuropilin-1 (NRP-1)is ahub receptor that plays an essential role in angiogenesis and vascular permeability. It is over-expres sed in the new blood vessels grown by tumor cells and is atarget for anti-tumor treatment s. Peptides that expose the consensus sequence R/K/ XXR/K at the C-terminus (C-end...
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| Publicado no: | J Struct Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6146283/ https://ncbi.nlm.nih.gov/pubmed/23462097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.02.006 |
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