Oophorectomy Reduces Estradiol Levels and Long-Term Spontaneous Neurovascular Recovery in a Female Rat Model of Focal Ischemic Stroke

Although epidemiological evidence suggests significant sex and gender-based differences in stroke risk and recovery, females have been widely under-represented in preclinical stroke research. The neurovascular sequelae of brain ischemia in females, in particular, are largely uncertain. We set out to...

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Publicat a:Front Mol Neurosci
Autors principals: Bazzigaluppi, Paolo, Adams, Conner, Koletar, Margaret M., Dorr, Adrienne, Pikula, Aleksandra, Carlen, Peter L., Stefanovic, Bojana
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146137/
https://ncbi.nlm.nih.gov/pubmed/30271324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00338
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