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Design and Inference for 3-Stage Bioequivalence Testing with Serial Sampling Data

A bioequivalence test is to compare bioavailability parameters, such as the maximum observed concentration (C(max)) or the area under the concentration-time curve (AUC), for a test drug and a reference drug. During the planning of a bioequivalence test, it requires an assumption about the variance o...

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Detalhes bibliográficos
Publicado no:Pharm Stat
Main Authors: Yan, Fangrong, Zhu, Huihong, Liu, Junlin, Jiang, Liyun, Huang, Xuelin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146059/
https://ncbi.nlm.nih.gov/pubmed/29726096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1865
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