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Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that causes serious infections in immunocompromised individuals and cystic fibrosis patients. ExoS and ExoT are two homologous bifunctional Type III Secretion System (T3SS) virulence factors that induce apoptosis in target host cells....

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kaminski, Amber, Gupta, Kajal H., Goldufsky, Josef W., Lee, Ha Won, Gupta, Vineet, Shafikhani, Sasha H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145893/
https://ncbi.nlm.nih.gov/pubmed/30232373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32491-2
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